Insulin resistance linked to treatment-refractory bipolar disorder

Patients with bipolar disorder who are insulin resistant are likely to also be refractory to mood-stabilizing treatment, report researchers.  This important idea can play a huge role in treating diabetic bipolar patients, providing a reason why medications may not work as well as they would on a control group… “We may find that unless we identify and treat underlying insulin resistance in patients with refractory bipolar disorder, these patients may remain unwell.”

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