Nov 1

Bipolar Patients’ Brain Cells Predict Response to Lithium

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Recent studies show that the brain cells of patients with bipolar disorder are more sensitive to stimuli than other people’s brain cells.   “Researchers hadn’t all agreed that there was a cellular cause to bipolar disorder,” says Rusty Gage, a professor in Salk’s Laboratory of Genetics. “So our study is important validation that the cells of these patients really are different.”

The finding is among the first to show at a cellular level how the disorder affects the brain. Moreover, it reveals why some patients respond to treatment with lithium while others don’t.

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