Antidepressants can increase depression & mood cycling in rapid-cycling bipolar disorder patients

Antidepressants are the most commonly prescribed class of medication for patients with Bipolar Disorder.  For those suffering from Rapid Cycling Bipolar Disorder (about 25% of Bipolar patients), these medications may work to bring them out of a depressive episode.  However studies show that they may also increase the frequency and intensity of manic and depressive episodes.

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