Herpesvirus may lead to bipolar, depression

Scientists have discovered the human herpesvirus HHV-6 in the neurons of people who lived with bipolar or severe depression. According to the National Institute of Mental Health (NIMH), 4.4 percent of the population of the United States will have bipolar disorder at one point in their lives. While the precise causes of such, often debilitating, … Read more

Aggression among 216 patients with a first-psychotic episode of bipolar I disorder

Aggression was identified in 23/216 subjects (10.6%). It was associated significantly with recent suicide attempt (OR = 4.86), alcohol abuse (OR = 3.63), learning disability (OR = 3.14), and initial manic episode (OR = 2.59), but not with age, sex, onset-type, personality disorder, time to recovery, or functional status. Click here to read the full article.

Comorbid Bipolar Disorder and Substance Abuse: A Challenge to Diagnose and Treat

Comorbid bipolar disorder and substance use disorder are frequently the rule rather than the exception.1 Bipolar disorder has among the highest rates of comorbidities, including anxiety disorders, obsessive compulsive disorder, impulse control disorders, eating disorders, cardiovascular and respiratory disorders, and sleep apnea.1 Not only are comorbid bipolar disorder and substance use disorder difficult to manage, but they also … Read more

The Effects of Sleep Loss on the Risk for Postpartum Psychosis in Bipolar Disorder

The perinatal period is associated with increased vulnerability to new-onset severe mental illness. Postpartum psychosis, for example, affects an estimated 1 in 1000 parous women in the general population and 20% to 30% of those with bipolar disorder. Research investigating the etiology of postpartum psychosis has identified immune dysregulation, genetic factors, and primiparity as potential … Read more

Bipolar Disorder in the Perinatal Period: No Consensus on Treatment

Given the frequency with which bipolar disorder relapses occur, the perinatal period may be a precarious time for mother and baby.1 In an effort to reconcile differences among different bipolar disorder guidelines, Graham and colleagues sought to decipher the recommendations on bipolar disorder in the perinatal period by reviewing 11 international guidelines published from 2005 … Read more

Probiotics Lower Rehospitalization Rates in Bipolar Disorder

Probiotics lowered the rate of rehospitalization after a manic episode, according to a small controlled trial released this month. This marks the first clinical trial of probiotics in bipolar disorder, and it builds on previous research that has found promise for these “healthy bacteria” in depression, anxiety, cognition, and autism. Click here to read the … Read more

Getting to the Root of the Problem: Stem Cells Are Revealing New Secrets about Mental Illness

Millions of Americans who suffer from bipolar disorder depend on lithium. The medication has been prescribed for half a century to help stabilize patients’ moods and prevent manic or depressive episodes. Yet what it does in the brain—and why it does not work for some people—has remained largely mysterious. Click here to read the full … Read more

A new path into bipolar disorder comes to light

Bipolar Disorder (BD) is a multifactorial brain disorder in which patients experience radical shifts in mood and undergo periods of depression followed by periods of mania. It has been known for some time that both environmental and genetic factors play important roles in the disease. For instance, being exposed to high levels of stress for … Read more