Bipolar Patients’ Brain Cells Predict Response to Lithium

Recent studies show that the brain cells of patients with bipolar disorder are more sensitive to stimuli than other people’s brain cells.   “Researchers hadn’t all agreed that there was a cellular cause to bipolar disorder,” says Rusty Gage, a professor in Salk’s Laboratory of Genetics. “So our study is important validation that the cells of these … Read more

MoodNetwork Seeks New Depression and Bipolar Treatments

MoodNetwork is the first online patient-powered research network for depression and bipolar disorder (mood disorders). MoodNetwork aims to bring together 50,000 participants who have experienced mood disorders, and their friends and families, to collaborate with researchers and clinicians. “Depression and bipolar disorder affect millions of people, but the treatments available, while helpful for many, are … Read more

Antidepressants can increase depression & mood cycling in rapid-cycling bipolar disorder patients

Antidepressants are the most commonly prescribed class of medication for patients with Bipolar Disorder.  For those suffering from Rapid Cycling Bipolar Disorder (about 25% of Bipolar patients), these medications may work to bring them out of a depressive episode.  However studies show that they may also increase the frequency and intensity of manic and depressive … Read more

High-res MRI links cerebellum to bipolar disorder

A different type of MRI has given researchers an unprecedented look at previously unrecognized differences in the brains of people with bipolar disorder, a new study from the University of Iowa reports. Specifically, the findings reveal differences in the white matter of patients’ brains and in the cerebellum, an area of the brain not previously … Read more